Vials drop from the The Vaal Omnitect in the The Temple of Atzoatl, and can be used to upgrade specific unique items to make them more powerful.
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Chronicle of Atzoatl
 Portal: The Temple of Atzoatl 
Area Level: 1 
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Stack Size: 1 / 10 
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Stack Size: 1 / 10 
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Stack Size: 1 / 10 
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Stack Size: 1 / 10 
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| Vial | Original item | Upgraded item | 
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| Vial of Awakening | Apep’s Slumber | Apep’s Supremacy | 
| Vial of Consequence | Coward’s Chains | Coward’s Legacy | 
| Vial of Dominance | Architect’s Hand | Slavedriver’s Hand | 
| Vial of Fate | Story of the Vaal | Fate of the Vaal | 
| Vial of Summoning | Mask of the Spirit Drinker | Mask of the Stitched Demon | 
| Vial of the Ritual | Dance of the Offered | Omeyocan | 
| Vial of Transcendence | Tempered Flesh | Transcendent Flesh | 
| Tempered Spirit | Transcendent Spirit | |
| Tempered Mind | Transcendent Mind | |
| Vial of Sacrifice | Sacrificial Heart | Zerphi’s Heart | 
| Vial of the Ghost | Soul Catcher | Soul Ripper |