Strongboxes are a special type of chest found throughout Wraeclast. When opened, a strongbox will release groups of monsters to surround and attack the character. Only once all of the ambushing monsters are slain will a strongbox relinquish its loot. The monsters released by a strongbox also drop loot and grant experience when killed.
Oba's Cursed Trove(search). It is a unique Underground Sea Map. The final area contains no monsters and instead contains five Strongboxes:

| Name | Description |
|---|---|
| Perandus Bank Jeweller's Strongbox | Guarded by 3 Rogue Exiles Contains 3 additional Unique Items Contains (3–5) additional Magic Items Contains (4–7) additional Rare Items Contains no other Items |
| Kaom's Cache Armourer's Strongbox | Guarded by 3 Rare Monsters chest delay drops until daemons finish [1] Contains an additional Kaom Item Guarded by the Ancestors' Power Contains (6–10) additional Rare Items Contains no other Items |
| Empyrean Apparatus Cartographer's Strongbox | Guarded by 5 Rare Monsters chest delay drops until daemons finish [1] Contains 3 additional Unique Maps Contained Items have (1–20)% Quality Contains no other Items |
| Oba's Prized Cache Jeweller's Strongbox | Contains (3–4) additional Rare Items Contains (3–4) additional Magic Items |
| Oba's Riches Arcanist's Strongbox | Contains (4–5) additional Items |
| Oba's Glittering Stash Gemcutter's Strongbox | Contains (6–7) additional Items Contained Items have (4–6)% Quality |
| Grandmaster's Gemcutting Cache Grandmaster's Cache | Contained Items have (1–15)% Quality Contained Gems have Experience Contains (4–5) additional Items map disable chest drop scaling [1] |
| Grandmaster's Arcanist Cache Grandmaster's Cache | Contains (6–10) additional Items map disable chest drop scaling [1] |
| Grandmaster's Cartography Cache Grandmaster's Cache | Contains (1–3) additional Item Contains (1–3) additional Magic Item Contains (1–3) additional Rare Item Contained Items have (1–20)% Quality map disable chest drop scaling [1] |
| Grandmaster's Ornate Cache Grandmaster's Cache | (2500–3500)% increased Rarity of Contained Items (50–80)% increased Quantity of Contained Items Contains (4–6) additional Rare Items map disable chest drop scaling [1] +2 Chest level |
| Grandmaster's Treasury Grandmaster's Cache | Contains an additional Unique Item (30–40)% increased Quantity of Contained Items (800–1200)% increased Rarity of Contained Items map disable chest drop scaling [1] +2 Chest level |
| Grandmaster's Trove Grandmaster's Cache | (30–40)% increased Quantity of Contained Items (800–1200)% increased Rarity of Contained Items Contains (6–10) additional Rare Items of the same type map disable chest drop scaling [1] +2 Chest level |
| Grandmaster's Corrupted Cache Grandmaster's Cache | Contains (2–3) extra Vaal Gems (30–40)% increased Quantity of Contained Items (800–1200)% increased Rarity of Contained Items Contains (3–5) extra Vaal Fragments map disable chest drop scaling [1] +2 Chest level |
| Grandmaster's Large Cache Grandmaster's Cache | (2000–2500)% increased Rarity of Contained Items (100–150)% increased Quantity of Contained Items map disable chest drop scaling [1] +2 Chest level |
| Strange Barrel Strongbox | chest delay drops until daemons finish [1] chest number of additional spider uniques to drop [1] Spreads Caustic Ground chest play warning sound [1] |
| Deshret's Storm Blacksmith's Strongbox | Contained Weapons are Animated Guarded by a stream of Monsters Contains (6–10) additional Rare Maraketh Weapons Contained Items are fully Linked Contained Items have an additional Socket |
| Ashes of the Condemned Strongbox | Guarded by 3 Rare Monsters chest delay drops until daemons finish [1] Guarded by a stream of Tormented Spirits (40–80)% increased Quantity of Contained Items (1800–2400)% increased Rarity of Contained Items |
| Mutewind Cache Strongbox | Guarded by a Mutewind Warband Contains an additional Mutewind Unique Item (80–100)% increased Quantity of Contained Items +(3–5) Chest level |
| Redblade Cache Strongbox | Guarded by a Redblade Warband Contains an additional Redblade Unique Item (80–100)% increased Quantity of Contained Items +(3–5) Chest level |
| Brinerot Cache Strongbox | Guarded by a Brinerot Warband Contains an additional Brinerot Unique Item (80–100)% increased Quantity of Contained Items +(3–5) Chest level |
| Renegades Cache Strongbox | Guarded by a Renegade Warband Contains an additional Renegade Unique Item (80–100)% increased Quantity of Contained Items +(3–5) Chest level |
| The Plaguemaw's Offering Arcanist's Strongbox | Contains 5 additional Items |
| Atziri's Vessel Vaal Vessel | map disable chest drop scaling [1] |
| Breach Box RENAME ME | Contains (4–5) additional Items |
| The Maelström Cell Diviner's Strongbox | Guarded by Dario, the Living Void Guarded by waves of Void Constructs chest delay drops until daemons finish [1] Contains additional Divination Cards that give Shaper or Elder items Contains (1–10) Divination Card that has a Full Stack number of (1–13) Contains no other Items |
| Weylam's War Chest Arcanist's Strongbox | Contains (20–30) additional Items chest delay drops until daemons finish [1] Contains an additional Pirate Unique item Guarded by a stream of Ghost Pirates Guarded by the Maiden of the Black Crest |
| Legacy Relic Relic Vault | chest drop reliquary items [1] |
| Timeworn Chest Relic Vault | chest drop reliquary items [2] |
| Vaal Repository Relic Vault | chest drop reliquary items [3] |
| Forgotten Guilt Relic Vault | chest drop reliquary items [4] |
| Visceral Remnant Relic Vault | chest drop reliquary items [5] |
| Shiny Toy Box Relic Vault | chest drop reliquary items [6] |
| Archive Cache Relic Vault | chest drop reliquary items [7] |
| What Little Remains Relic Vault | chest drop reliquary items [8] |
| A Father's Love Relic Vault | chest drop reliquary items [9] |
| Silent Legacy Relic Vault | chest drop reliquary items [10] |
| Voidborn Chest Relic Vault | chest drop reliquary items [11] |
| Book Stand Strongbox Diviner's Strongbox | (30–60)% increased Quantity of Contained Items |
| Gifts of the Sacrificed Vaal Reliquary | Guarded by Ixtolatl, Artisan of Sacrifice Guarded by waves of Vaal Monsters chest delay drops until daemons finish [1] |
| Gifts of the Red Queen Vaal Reliquary | Guarded by Mahuatzi, Artisan of Desire Guarded by waves of Vaal Monsters chest delay drops until daemons finish [1] |

Like most other unique items, it is possible to craft a unique strongbox using an
Orb of Chance on a normal strongbox with the corresponding base type.
| Item | Stats |
|---|---|
| Area contains 3 extra Strongboxes | |
| Area contains 4 extra Strongboxes | |
| Area contains 5 extra Strongboxes | |
| Area contains 9 extra Strongboxes |
| Count | Name | Category | Description |
|---|---|---|---|
| 1 | Twice Tempted | Notable |
|
| 4 | Strongbox Additional Pack Chance | Normal |
|
| Count | Name | Category | Description |
|---|---|---|---|
| 1 | Tamper-Proof | Notable |
|
| 3 | Strongbox Chance to be Reopenable | Normal |
|
| 1 | Secret Operations | Notable |
Reminder Text: |
| Count | Name | Category | Description |
|---|---|---|---|
| 1 | Strongbox Item Quantity | Normal |
|
| 1 | Vault of Mysteries | Notable |
|
| 2 | Arcanist's Strongbox Chance | Normal |
|
| 2 | Cartographer's Strongbox Chance | Normal |
|
| 2 | Diviner's Strongbox Chance | Normal |
|
| 1 | Backup Cache | Notable |
|
| 1 | Concealed Logistics | Notable |
|