Defy Pain is a Ascendancy Passives for Berserker.
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Defiance is a notable passive skill that grants increased attack damage and additional chance to block attack damage with a shield equipped. It also grants increased defences (armour rating, evasion rating and energy shield) from equipped shields.
How does Berserker’s “Defy Pain” work? The 10-stack damage is reduced by armour and physical reduction (i.e. endurance charges), but is it reduced by Reduced Reflect Damage Taken modifiers?
It is reflected damage that you are taking, yes.
Are there ways to increase the damage it deals?
You can increase how much damage you take from it with damage taken modifiers, such as being shocked. The amount of damage it tries to deal is fixed.