Yes, XDefiant does support crossplay. This feature allows players on PC, PlayStation 5, and Xbox Series X|S to play together. Crossplay is enabled by default, but it can be turned off in the game settings if preferred.
Additionally, XDefiant supports cross-progression, meaning players can maintain their progress and items across different platforms as long as they use the same Ubisoft account. Here is the guide for The Premier XDefiant Boosting Service.
For those concerned about input method differences, XDefiant uses input-based matchmaking to ensure fairness, so players using controllers won’t be matched with those using a mouse and keyboard, unless they are in a mixed-input party.